Preventing the Progression of Osteoarthritis (OA) of the Knee by Injections of Autologous Stem Cells

This project investigates the concept one medicine to prevent OA and uses clinical veterinary cases to investigate the use of stem cell injections into the knee of animals with OA as a proof of concept for further investigation in human clinical trials. The animals are clinical cases and have OA, which is essentially similar to that seen in humans. Different sources of stem cells are being investigated, which include bone marrow derived stem cells and adipose derived stem cells. After charaterisation these cells are injected back into the knee joint and the results assessed.

So far over 40 clinical animals have been treated with with either adipose derived or bone marrow derived stem cells and the results are being assessed.