Phase 3 study to investigate the effects of BAN2401 in AD patients.

A Placebo-Controlled, Double-Blind, Parallel-Group, 18-Month Study With an Open-Label Extension Phase to Confirm Safety and Efficacy of BAN2401 in Subjects With Early Alzheimer’s Disease

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Dementia
Specialty: Dementias
Recruitment Site: Marc

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WN39658 - Gantenerumab in patients with prodromal to mild AD

GRADUATE - Gantenerumab in patients with prodromal to mild AD

Trust Name: University Hospital Southampton NHS Foundation Trust
Contact name: R&D department
Condition: Dementia
Specialty: Dementias
Recruitment Site: Southampton General Hospital

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BN40423 Generation HD 1

A RANDOMIZED, MULTICENTER, DOUBLE-BLIND, PLACEBO-CONTROLLED, PHASE III CLINICAL STUDY TO EVALUATE THE EFFICACY AND SAFETY OF INTRATHECALLY ADMINISTERED RO7234292 (RG6042) IN PATIENTS WITH MANIFEST HUNTINGTON'S DISEASE

Trust Name: University Hospital Southampton NHS Foundation Trust
Contact name: R&D department
Condition: Huntington's disease
Specialty: Neurological disorders
Recruitment Site: Southampton General Hospital

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Delphia study

A Placebo-Controlled, Double-Blind, Parallel-Group, Randomized, Study To Evaluate the Efficacy, Safety and Tolerability of E2027 in Subjects With Dementia With Lewy Bodies (Delphia)

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Dementia
Specialty: Dementias
Recruitment Site: Marc

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NOSTRA-Traumatic Brain Injury-3559/0001

Efficacy of VAS203 in patients with moderate and severe traumaticbrain injury (NOSTRA Phase III trial) – a confirmatory, placebocontrolled,randomised, double blind, multi-centre study.

Trust Name: University Hospital Southampton NHS Foundation Trust
Contact name: R&D department
Condition: Other
Specialty: Neurological disorders
Recruitment Site: Southampton General Hospital

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RESIST(TNF) - RhEumatoid arthritiS, medIcation and memory STudy

TNF inhibitors in the prevention of Alzheimer’s disease

Trust Name: University Hospital Southampton NHS Foundation Trust
Contact name: R&D department
Condition: Parkinson's disease
Specialty: Neurological disorders
Recruitment Site: Southampton General Hospital

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Phase 3 of AVP-786 in Alzheimer’s dementia patients with agitation

A Phase 3, multicenter, randomized, double-blind, placebo-controlled, parallel-design study to assess the efficacy, safety, and tolerability of AVP-786 (deudextromethorphan hydrobromide[d6-DM]/ quinidine sulfate [Q]) for the treatment of agitation in patients with dementia of the Alzheimer’s type.

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Dementia
Specialty: Dementias
Recruitment Site: Marc

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CASTLE TRIAL v1.0

Randomised factorial design controlled trial comparing carbamazepine, levetiracetam or active monitoring combined with or without sleep behaviour intervention in treatment naive children with rolandic epilepsy

Trust Name: University Hospital Southampton NHS Foundation Trust
Contact name: R&D department
Condition: Epilepsy
Specialty: Neurological disorders
Recruitment Site: Southampton General Hospital

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PriDem: Primary care led support in dementia: Developing best practice

Primary care led post diagnostic dementia care: developing evidence-based, person-centred sustainable models for future care (PriDem)

Trust Name: University Hospital Southampton NHS Foundation Trust
Contact name: R&D department
Condition: Dementia
Specialty: Dementias
Recruitment Site: Southampton General Hospital

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Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: University Hospital Southampton NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: Southampton General Hospital

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STRATIFY

Brain network based stratification of reinforcement-related disorders

Trust Name: University Hospital Southampton NHS Foundation Trust
Contact name: R&D department
Condition: Depression
Specialty: Mental Health
Recruitment Site: Southampton General Hospital

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Measuring Cognitive and Behavioural Change in ALS

Cognitive and behavioural impairment in Amyotrophic Lateral Sclerosis: Comparing measures and validating revised consensus diagnostic criteria for Amyotrophic Lateral Sclerosis-Frontotemporal Spectrum Disorder

Trust Name: University Hospital Southampton NHS Foundation Trust
Contact name: R&D department
Condition: Motor neurone disease
Specialty: Neurological disorders
Recruitment Site: Southampton General Hospital

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CASTLE TRIAL v1.0

Randomised factorial design controlled trial comparing carbamazepine, levetiracetam or active monitoring combined with or without sleep behaviour intervention in treatment naive children with rolandic epilepsy

Trust Name: The Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust
Contact name: R&D department
Condition: Epilepsy
Specialty: Neurological disorders
Recruitment Site: Royal Bournemouth General Hospital

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AD GENETICS

Detecting Susceptibility Genes for Late-onset Alzheimer's disease

Trust Name: University Hospital Southampton NHS Foundation Trust
Contact name: R&D department
Condition: Dementia
Specialty: Dementias
Recruitment Site: Southampton General Hospital

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MND Register for England, Wales and Northern Ireland

MND Register for England, Wales and Northern Ireland

Trust Name: University Hospital Southampton NHS Foundation Trust
Contact name: R&D department
Condition: Motor neurone disease
Specialty: Neurological disorders
Recruitment Site: Southampton General Hospital

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Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: Winchester CMHT OPMH

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RESIST(TNF) - RhEumatoid arthritiS, medIcation and memory STudy

TNF inhibitors in the prevention of Alzheimer’s disease

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Parkinson's disease
Specialty: Neurological disorders
Recruitment Site: Marc

Read more

Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: West New Forest CMHT Amh

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Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: Western Community Hospital

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Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: Petersfield CMHT

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Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: Southern Health NHS Foundation Trust

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Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: The Parkway Centre

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Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: Parklands Hospital

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Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: Newtown House

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Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: Melbury Lodge

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Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: Moorgreen Hospital

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Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: Fareham & Gosport

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Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: Horsefair Mews

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Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: College Keep

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Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: Desborough House

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Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: Bridge Centre

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Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: Cannon House

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Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: Aerodrome House

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Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: Andover War Memorial Hospital

Read more

Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: April House

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AD GENETICS

Detecting Susceptibility Genes for Late-onset Alzheimer's disease

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Dementia
Specialty: Dementias
Recruitment Site: Marc

Read more

STRATIFY

Brain network based stratification of reinforcement-related disorders

Trust Name: Southern Health NHS Foundation Trust
Contact name: R&D department
Condition: Depression
Specialty: Mental Health
Recruitment Site: College Keep

Read more

STRATIFY

Brain network based stratification of reinforcement-related disorders

Trust Name: Solent NHS Trust
Contact name: R&D department
Condition: Depression
Specialty: Mental Health
Recruitment Site: St Mary's Health Campus

Read more

Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Solent NHS Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: St Mary's Health Campus

Read more

CASTLE TRIAL v1.0

Randomised factorial design controlled trial comparing carbamazepine, levetiracetam or active monitoring combined with or without sleep behaviour intervention in treatment naive children with rolandic epilepsy

Trust Name: Salisbury NHS Foundation Trust
Contact name: R&D department
Condition: Epilepsy
Specialty: Neurological disorders
Recruitment Site: Salisbury District Hospital

Read more

AD GENETICS

Detecting Susceptibility Genes for Late-onset Alzheimer's disease

Trust Name: Solent NHS Trust
Contact name: R&D department
Condition: Dementia
Specialty: Dementias
Recruitment Site: St Mary's Health Campus

Read more

Measuring Cognitive and Behavioural Change in ALS

Cognitive and behavioural impairment in Amyotrophic Lateral Sclerosis: Comparing measures and validating revised consensus diagnostic criteria for Amyotrophic Lateral Sclerosis-Frontotemporal Spectrum Disorder

Trust Name: Salisbury NHS Foundation Trust
Contact name: R&D department
Condition: Motor neurone disease
Specialty: Neurological disorders
Recruitment Site: Salisbury District Hospital

Read more

PriDem: Primary care led support in dementia: Developing best practice

Primary care led post diagnostic dementia care: developing evidence-based, person-centred sustainable models for future care (PriDem)

Trust Name: Salisbury NHS Foundation Trust
Contact name: R&D department
Condition: Dementia
Specialty: Dementias
Recruitment Site: Salisbury District Hospital

Read more

Measuring Cognitive and Behavioural Change in ALS

Cognitive and behavioural impairment in Amyotrophic Lateral Sclerosis: Comparing measures and validating revised consensus diagnostic criteria for Amyotrophic Lateral Sclerosis-Frontotemporal Spectrum Disorder

Trust Name: Poole Hospital NHS Foundation Trust
Contact name: R&D department
Condition: Motor neurone disease
Specialty: Neurological disorders
Recruitment Site: Poole General Hospital

Read more

PriDem: Primary care led support in dementia: Developing best practice

Primary care led post diagnostic dementia care: developing evidence-based, person-centred sustainable models for future care (PriDem)

Trust Name: Poole Hospital NHS Foundation Trust
Contact name: R&D department
Condition: Dementia
Specialty: Dementias
Recruitment Site: Poole General Hospital

Read more

CASTLE TRIAL v1.0

Randomised factorial design controlled trial comparing carbamazepine, levetiracetam or active monitoring combined with or without sleep behaviour intervention in treatment naive children with rolandic epilepsy

Trust Name: Poole Hospital NHS Foundation Trust
Contact name: R&D department
Condition: Epilepsy
Specialty: Neurological disorders
Recruitment Site: Poole General Hospital

Read more

MND Register for England, Wales and Northern Ireland

MND Register for England, Wales and Northern Ireland

Trust Name: NHS North East Hampshire and Farnham CCG
Contact name: R&D department
Condition: Motor neurone disease
Specialty: Neurological disorders
Recruitment Site: Phyllis Tuckwell Mem.Hosp

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MND Register for England, Wales and Northern Ireland

MND Register for England, Wales and Northern Ireland

Trust Name: Poole Hospital NHS Foundation Trust
Contact name: R&D department
Condition: Motor neurone disease
Specialty: Neurological disorders
Recruitment Site: Poole General Hospital

Read more

CASTLE TRIAL v1.0

Randomised factorial design controlled trial comparing carbamazepine, levetiracetam or active monitoring combined with or without sleep behaviour intervention in treatment naive children with rolandic epilepsy

Trust Name: Hampshire Hospitals NHS Foundation Trust
Contact name: R&D department
Condition: Epilepsy
Specialty: Neurological disorders
Recruitment Site: Royal Hampshire County Hospital

Read more

AD GENETICS

Detecting Susceptibility Genes for Late-onset Alzheimer's disease

Trust Name: Isle of Wight NHS Trust
Contact name: R&D department
Condition: Dementia
Specialty: Dementias
Recruitment Site: St Mary's Hospital

Read more

Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Dorset Healthcare University NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: Boscombe Community Hospital

Read more

Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Trust Name: Dorset Healthcare University NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety
Specialty: Mental Health
Recruitment Site: Dorset Healthcare University NHS Foundation Trust

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Alleviating Specific Phobias Experienced by Children Trial (ASPECT)

A non-inferiority randomised controlled trial comparing the clinical and cost-effectiveness of one session treatment (OST) with multi-session cognitive behavioural therapy (CBT) in children with specific phobias

Trust Name: Dorset Healthcare University NHS Foundation Trust
Contact name: R&D department
Condition: Anxiety - social
Specialty: Mental Health
Recruitment Site: Dorset Healthcare University NHS Foundation Trust

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STRATIFY

Brain network based stratification of reinforcement-related disorders

Trust Name: Dorset Healthcare University NHS Foundation Trust
Contact name: R&D department
Condition: Depression
Specialty: Mental Health
Recruitment Site: Dorset Healthcare University NHS Foundation Trust

Read more

AD GENETICS

Detecting Susceptibility Genes for Late-onset Alzheimer's disease

Trust Name: Dorset Healthcare University NHS Foundation Trust
Contact name: R&D department
Condition: Dementia
Specialty: Dementias
Recruitment Site: Boscombe Community Hospital

Read more